Abstract:

The aim of the following research work is the comparative assessment of the ultrasound methods of the biological age determination among patients with the isolated run of the arterial hypertension and its compatibility with the type 2 diabetes mellitus, chronic obstructive pulmonary disease against hypercholesterolemia. The vascular age assessment has been held according to age gradation of the thickness of the intima – media common carotid artery complex suggested by the Society of Cardiology of the Russian Federation (2009). The biological age has been defined by the echocardiography method of the Perm State Medical Academy ontogenesis laboratory. 901 patients of four age groups (40-49; 50-59; 60-69; 70-79 years old) have been examined. 248 apparently healthy patients made up the control set (group 1); 63 patients had identified hypercholesterolemia without co-morbidity (group 2); 368 patients had the isolated run of hypertension and hypercholesterolemia (group 3); 161 patients showed up the combination of hypertension, diabetes mellitus and hypercholesterolemia (group 4); 61 patients showed up the combination of hypertension, chronic obstructive pulmonary disease and hypercholesterolemia (group 5). In comparison with the echocardiography method, the ultrasound determination of the thickness of the intima – media common carotid artery complex is an objective criterion which makes it possible not just to assess the biological age, but the risk level of heart attack and stroke origin.

Keywords: biological age, arterial hypertension, type 2 diabetes mellitus, chronic obstructive pulmonary disease, common carotid artery intima-media thickness