In last year the very big interest to the problem of androgen deficiency take place (ADAM). The purpose of this study was to examine the VAD men in connection with the development of their cardiovascular disease and subsequent development of clinical and laboratory biochemical criteria to reduce gonadal function in this patient group. The study included 314 patients. The development of cardiovascular disease VAD is starting to influence the age of 40-50 years. Biochemical criteria for VAD in the presence of cardiovascular disease characterized by average levels of total testosterone level 2,28-2,29 ng / ml in serum free testosterone - 60,1-68,1 pg / ml. ADAM in association with cardiovascular diseases, is characterized by symptoms such as general weakness, difficulty in falling asleep and daytime sleepiness, irritability, panic attacks, the formation of sense of" lifelessness’’, as well as decreased libido, decrease in morning erections,decrease in frequency of sexual activity.