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Ãëàâíàÿ / Íîìåðà æóðíàëîâ /¹ 2, 2014

Pharmaceutical Sciences
ACTIVATION OF ANTI-INFLAMMATORY SYSTEM OF THE BODY BY BIOFLAVONOID TREATMENT OF CHRONIC VENOUS INSUFFICIENCY IN ELDERLY PEOPLE
Prashchayeu K.I. 3, Shamaraeva I.V. 2, Kuzmina G.I. 1, Tarasenko A.V. 1, Bessarabov V.I. 4

1. Kyiv National University of Technologies and Design, Industrial Pharmacy Department, Kyiv, Ukraine
2. "Gerontology" Research Medical Center, Moscow, Russia
3. "Gerontology" Research Medical Center, Moscow, Russia
4. "Gerontology" Research Medical Center, Moscow, Russia

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The article discusses the impact of therapy by micronized purified flavonoid fraction (Mpff) Diosmin + Hesperidin on anti-inflammatory system of the body in chronic venous insufficiency (CVI) in the elderly. Showed that in the elderly compared with the average age was significantly (p<0,05) reduced anti-inflammatory activity of the organism (as measured by the level of IL-4 in the serum). However, increasing polymorbidity leads to an increase of this parameter in the elderly and in middle age. Established that pharmacotherapy Mpff Diosmin + Hesperidin for 30 days leads to the activation of anti-inflammatory system of the body, resulting in a significant increase of the concentration of IL-4 in the serum of patients with CVI and CVI + type 2 diabetes mellitus (p<0,05) compared to values before treatment.

Keywords: Diosminum, Hesperidinum, chronic venous insufficiency, IL-4

Reference

Prashchayeu K.I. 3, Shamaraeva I.V. 2, Kuzmina G.I. 1, Tarasenko A.V. 1, Bessarabov V.I. 4 ACTIVATION OF ANTI-INFLAMMATORY SYSTEM OF THE BODY BY BIOFLAVONOID TREATMENT OF CHRONIC VENOUS INSUFFICIENCY IN ELDERLY PEOPLE // ÃÅÐÎÍÒÎËÎÃÈß. – 2014. – ¹ 2;
URL: gerontology.esrae.ru/6-79 (Date Access: 04.12.2024).

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